Science has pointed out to the fact that CBD could be effective in the treatment of endocrine disorders. But of course, CBD’s effectiveness in treating endocrine disorders is not unconnected to the role of the endocannabinoid system of the body. It is worthy to note that the endocannabinoid system does not only play the vital role of regulating the body’s activities including homeostasis, but also, its receptors are located in regions of the brain that send signals to the thyroid gland which produces many hormones.
The endocrine system is an important network of glands in the body that plays the crucial role of producing and releasing hormones that help control many important body functions. For instance, the endocrine system controls the body’s ability to convert calories that powers both the cells and organs of the body.
The endocrine system controls many bodily functions, including how the heart beats, how the bones and tissues grow as well as the ability to make babies. It also plays a vital role in whether or not people develop certain diseases like diabetes, thyroid disorders, growth disorders, sexual dysfunctions as well as hormone related disorders.
There are many endocrine glands in the body, including adrenal glands, ovaries, parathyroid, pineal gland, pituitary gland, testes, thymus, thyroid, etc. Each of these glands release specific hormones into the bloodstream, that helps control many body processes.
Endocrine disorders are typically grouped into two categories, and include hormonal imbalance and diseases such as nodules or tumors caused by the development of lesions.
Hormonal imbalance are typically caused by a number of factors, including problem with the endocrine feedback system, diseases/infections, injury or tumor to the endocrine gland, genetic disorders such as such as multiple endocrine neoplasia (MEN)/congenital as well as failure of a gland to stimulate another gland to release hormones.
There are many types of endocrine disorders and diabetes has been reported to be the most common in the USA. Other endocrine disorders nevertheless, include Cushing’s disease, adrenal insufficiency, gigantism, polycystic ovarian syndrome and hyperthyroidism.
The treatment for endocrine disorder can be complicated because a change in one hormone level can throw off another. This therefore explains why doctors often carry out routine blood work on patients to check for problems as well as to determine if medications or treatment plans should be adjusted.
A 2009 study that was published in the Journal of Endocrinology revealed that there are many CB1 receptors in the brain nerves and that they are involved in the hypothalamic-pituitary-thyroid axis as well as its regulation. Of course, this area is known to control hormone production by the thyroid gland.
Recent preclinical studies have also revealed that maintaining a healthy endocannabinoid system has great therapeutic benefits in endocrine disorders. This assertion can be explained by the fact that once the endocannabinoid system has a healthy tone, a person has better stress resilience as well as reduced residual post-traumatic anxiety, panic behaviors, and fears.
Some studies have also proven that CBD reduces anxiety by activating receptors outside CB2, thereby acting as an anxiolytic that mitigate fear and panic response to stress. Other studies have equally shown that CBD actually interacts with the endocrine system to affect sleep cycle, metabolism as well as sexual activity, whereas some other studies have even indicated that the endocannabinoids can control the proliferation of numerous types of endocrine cancer cells, thereby leading to antitumor effects.
Cannabinoids have been particularly proven to be able to inhibit cell growth and metastasis in oncological diseases such as thyroid, prostate and breast tumors.
A few studies have equally explored the relationship between CBD and diabetes, which is one of the most common endocrine disorders. The results from these studies have however suggested that CBD impacts pancreas function and insulin production, thereby influencing blood sugar levels.
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